Highest Rated Manga

Very few adolescent boys and girls have an onset of special abilities. Yuu Otosaka uses his ability unbeknownst to others in order to lead a satisfying school life. And then, a girl named Nao Tomori suddenly appears before him. Their encounter reveals the destiny for wielders of special abilities.

(Source: Official website)

Note: Volume 4 contains chapter 25.5.
Volume 6 contains an epilogue.

In a world where all feeling is artificial and where everyone is a potential drug addict, nothing has really changed: the excess is near at hand and very few substances are considered dangerous and put under strict control by a hygiene office, which has full power over the drug addicts who are in an extreme condition.

The main character is Kabu, a little peddler and heavily addicted. Used to any kind of hallucinogenic trip, he is able to feel
happiness through the ecstasy of the drug, while at the same time hypocritically hating those who gave birth to this society which has forced him to excess.
After an overdose caused by mixing two incompatible drugs, he spends his days looking for stimulants until he encounters an enigmatic man who offers him a new kind of illegal substance: UltraHeaven.
From that moment his incredible journey begins, where dream and reality are fused in an undivided world, causing him hysterical or joyful reactions and unrestrained pains.

But what really is UltraHeaven and who's really behind it? And who is the guru who is promoting meditation as a powerful way to influence the whole universe surrounding us?
With the help of a special amplifier helmet, Kabu starts a trip into the deep and hidden layers of his consciousness, diving into a nightmare he would otherwise never discover...

(Source: MU)

This series revolves around a ronin samurai named Senou Souichirou and his young neighbor Kankichi, the son of a carpenter.

The series Junjou Romantica series actually contain 3 main stories within them, which are loosely interconnected, with different couples as the main characters.
Junjou Romantica:
Misaki, struggling to pass his college entrance exams, is in need of a tutor to help pump up his failing grades. Unfortunately, his only option is the cool and sexy Akihiko Usami. Usami happens to be a famous boys’ love novelist, which doesn’t exactly float Misaki’s boat, especially since his main characters are “Akihiko” and “Takahiro,” the name of Misaki’s older brother and Usami’s childhood friend. Understandably, Misaki is pretty disgusted by the thought of someone using his older brother as his personal fantasy-material, but then after some tender loving from Usami, Misaki is also pretty confused. He may even be developing feelings for the older man...And when Takahiro introduces them to his lovely (female) fiancée, so begins the bumpy relationship of this odd couple, filled with comedy and pure romance. (Source: BLU manga)
Junjou Egoist: Kamijou Hiroki is a broken man, consumed by unrequited love for his childhood friend, Usami Akihiko (the writer character in Junjou Romantica). Along comes Kusama Nowaki, whose name "Nowaki" means "typhoon", an orphan working his way through life since middle school. Like the typhoon he is named for, he whirls into Hiroki's life and heart, blowing all resistance away before him.
Junjou Terrorist: As fate would have it, Professor Miyagi Yoh (whom Hiroki is working with as assistant professor), and Takatsuki Shinobu, a high school student, cross paths. Miyagi, when in high school, loved (and still cannot forget) a female teacher who had a terminal illness, is now faced with Shinobu, who just says whatever is on his mind. The wheel of destiny is beginning to turn once again...
Has another short story called Junjou Minimum in vol. 4, which in turn has a separate volume of its own.
(B-U)

Twelve years after her loved ones were brutally murdered at the annual family meeting, Ange Ushiromiya, now eighteen, is the sole heir of the Ushiromiya family. Ostracized by her peers, Ange seeks companionship in the pages of a diary left behind by her cousin, Maria. The diary offers a precious glimpse of Maria's world--her struggles at school, her friendship with stuffed--lion Sakutarou, and her fascination with magic. It's as if the diary contains the last remnants of Ange's dear cousin...and an opportunity for Ange to discover the magic within herself...

(Source: Yen Press)

Kemono Jihen is about a boy known as Dorota-bou who is avoided by the people who surround him, and Inugami, a detective who specializes in the occult. The story begins with Inugami arriving at the boy's town to investigate a case where many cattle are dying and their bodies rot in just one night.

(Source: Manga Tokyo)

The "youth pure love" story begins when three students in their third and final year of high school meet during a time when they are worried about paths for their futures. Waiting for them are sweet, painful, and heartrending days.

(Source: ANN)

Gangnam lost his parents from a fire and has turned blind from the incident. He wasn't able to see anything but a hallucination called Kkamjang. Is Kkamjang actually a hallucination or something more? 'Your scars, your two eyes, and... even your strength! I'll change everything for you.'

(Source: MU)

Priscilla Motia works as a sorceress at the mercenary corps, but she was once the only daughter of a count. Until her father died, and her stepmother made a fortune from selling their valuables to her divorced husband who was 10 years older...

In an accident while working as a mercenary, Priscilla got her hands on the Dragon Heart just before she dies... This is a chance to take back the 15 years that she lost! She is determined to go on a big adventure.

“You're back!"

But what awaited Priscilla was a huge debt caused by her evil divorced husband.

Seeking for revenge, Priscilla goes looking for Kian Rustin, the Black Death of the Battlefield for help and asks, “I have a favor to ask of you."

“What do you want me to do? Is this an assassination attempt?"

"Kian Rustin! Please be my husband."

So, will Priscilla be able to win both land and love?

(Source: Mangadex)

Five years ago, almost every villager of Ootsuka died due to a tragic plague. But mysteriously enough, three survivors: a girl and two boys, emerged. Now living in a church, the three live in isolation, hidden from those who may seek to find them. Shino, one of the survivors, has control over the power of Murasame, the blade of life. But when the imperial church seeks to take the Murasame for themselves, their peaceful life becomes a thing of the past...
(Source: Bliss)

The author, a high school teacher, recounts his 12 years on "night patrol" in Yokohama City, where he comes face to face with youth dealing with issues ranging from self-mutilation to drug abuse.
(Source: MU)

A spin-off of Nanatsu no Taizai showing how Ban and Elaine met in more detail.

In the land north of Britannia, there is a forest where humans are not allowed to go, and it is known as the "Fairy King's Forest." The one known as the Fairy King, Harlequin, has not been seen for 700 years. His younger sister Elaine guards the Fountain of Youth from human greed by herself. After many partings and 700 years of isolation, her tears are about to dry up. Then, a young man appears seeking the Fountain of Youth. That young man's name is Ban.

Over the course of seven days with Ban, Elaine's heart is healed. The distance between them closes, but...

(Source: ANN)

Lee Hoon is a 17 year old shut-in/highschool boy who wants to commit suicide, but can't decide on the method of his death so he wants to test all the various ideas he comes up with. Hooni is current living alone suicidally depressed over the debts left by his run away abusive drunk of a Father and the hospital bills racked up due to his now deceased Mother's illness, with very little savings he's also been unable to pay his rent for months, even at school he's bullied.

(Source: MU)

Takiko Okuda is a strong-willed girl living in the Taisho Era. She needs to be strong -- Oosugi, the one man she's ever loved, is a married man; her mother is terminally ill; and her father, Einosuke, has not been home in over a year. When at last Einosuke returns, it's with a notebook full of Chinese scribblings that seem more important to him than the death of his wife. Furious, Takiko steals away his completed translation -- "The Universe of the Four Gods" -- with the intention of tearing it to shreds, but the instant she opens it, she's surrounded by light... And it is said that this is how the legend of the Priestess of Genbu began.
(Source: ShoujoMagic)Included one-shot:
Volume 6: Ayashi no Ceres Gaiden

Naofumi Iwatani, an uncharismatic Otaku who spends his days on games and manga, suddenly finds himself summoned to a parallel universe! He discovers he is one of four heroes equipped with legendary weapons and tasked with saving the world from its prophesied destruction. As the Shield Hero, the weakest of the heroes, all is not as it seems. Naofumi is soon alone, penniless, and betrayed. With no one to turn to, and nowhere to run, he is left with only his shield. Now, Naofumi must rise to become the legendary Shield Hero and save the world!

(Source: One Peace)

A Korean NEET who lives day to day playing games turned into a girl all of sudden! What will he do?Bagel is Korean slang for a girl with a baby face and a glamorous (sexy) body.(Source: MU)

Just when an unemployed thirty-four-year-old otaku reaches a dead end in life and decides that it's time to turn over a new leaf—he gets run over by a truck and dies! Shockingly, he finds himself reborn into an infant's body in a strange new world of swords and magic.His new identity is Rudeus Grayrat, but he still retains the memories of his previous life. Follow Rudeus from infancy to adulthood, as he struggles to redeem himself in a wondrous yet dangerous world.

(Source: Seven Seas)

Kimi wa Girfriend is about a girl named Hatsune with a "bad mouth", for lack of a better description. She's kind-hearted, but her mouth spews the total opposite of what she means (which is probably due to the fact that she grew up with only male influence). And so she is seen as an arrogant, vulgar girl at her school, but all she wants is a girlfriend. Well, that is, until she gets accepted at the Maidens' Club, where she meets a guy named Kirie, with a somewhat unique habit that happens when a girl comes within a foot of him. And everyone says he's gay, even Hatsune. How will these two fare? Will Hatsune have a girlfriend at last? Will he be more than just a friend?
(Source: MU)