From all over Japan, Yankee Boys (hoodlums) full of dreams
and ambition gather in Gure Tokyo. Then Chagecha appears
with his unorthodox "Yanki", and changes everything!!

Starting up one year after the finale of the first series, the Maruhage Empire is reformed by former emperor Tsuru Tsurulina III into the Neo-Maruhage Empire, where the Hair Hunts resume and a new generation of powerful Hair Hunt generals are created. Bo-bobo, powering the abilities of his "Fist of the Nosehair" into its "True Theory" form, rejoins Beauty and the Hajike allies to take on the renewed Maruhage threat.
(Source: ANN)

In the year 300X, Earth is terrorized by the evil Maruhage Empire, which will stop at nothing to rid the entire population of their hair. But now, one afro-wearing man stands his way. He has the ability to communicate with other people's hair and use his own nasal hair to defeat the Maruhage Empire's bald henchmen. His name: Bobobo-bo Bo-bobo.