A teacher named Seiji Hasumi is loved by his students and respected by his peers. However, his outward charm masks his true nature. In reality, Hasumi is a psychopath who is unable to feel empathy for other human beings. Specifically, he has a severe antisocial personality disorder. Because of his mental condition, Hasumi chooses to deal with problems like bullying and overbearing “monster parents” the easy way, by systematically murdering his students/parents.

The story is set in Japan a millennium from now. Five children — the protagonist Saki, Satoru, Maria, Mamoru, and Shun — have been born and raised in a tranquil town that can be described as a utopia, overflowing with water and green foilage. The world is ruled by people who have the "cursed power" or the "gods' power" of telekinesis.
After a certain incident, Saki and the others come to realize the true nature of their world. Before long, they learn everything, including the bloody history that brought humanity to this state. The five throw themselves into life-threatening adventure and fighting to protect friends and a world on the brink of collapse.